Description: It turns out that individuals struggling with anorexia seem to have a narrower array of microbes in their gut than do people without the disorder. What might this observed relationship suggest?
Source: Today Health and Wellness
Date: October 6, 2015
Links: Article Link – http://www.sciencedaily.com/releases/2015/10/151005121310.htm
The Study: http://europepmc.org/abstract/med/26428446
In this study a small group of individuals struggling with anorexia were assessed at admission to a treatment facility and specifically had stool samples taken and assayed in order to determine the nature and complexity of the bacteria living in their gut. What was consistently found was that these individuals upon admission for treatment for anorexia had lower bacteria counts and less complexity in the types of bacteria found in their gut at admission. Further it was found upon discharge that the nature and complexity of the bacteria in their gut had increased significantly and move much closer to what would otherwise be considered normal levels. As you can imagine the authors speculate as to the nature and potential causal direction of this relationship will and whether or not it might suggest addition to the treatment of anorexia. While this might seem entirely correlational, has been quite a bit of work lately pointing to a relationship between the gut and the brain, referred to as the gut brain axis and suggesting what happens in the gut may have implications for what happens in the brain.
Questions for Discussion:
- Why might face-to-face interaction as opposed to social media use, email or texting be associated with lower depression scores? What is it about face-to-face contact that promotes well-being?
- Given that the sample in this study is comprised entirely of adults over the age of 50, what questions, if any, does this give rise to when you think about whether or not the results of the study could be generalized across the entire population (all ages)?
- How might the results of the study be different if it had been conducted among a typical young adult undergraduate population? Or would you expect the results to be similar and why?
References (Further Reading):
Susan C. Kleiman, Hunna J. Watson, Emily C. Bulik-Sullivan, Eun Young Huh, Lisa M. Tarantino, Cynthia M. Bulik, Ian M. Carroll. The Intestinal Microbiota in Acute Anorexia Nervosa and During Renourishment. Psychosomatic Medicine, 2015; 1 http://europepmc.org/abstract/med/26428446
Fetissov, S. O., & Dechelotte, P. (2011). The new link between gut–brain axis and neuropsychiatric disorders. Current Opinion in Clinical Nutrition & Metabolic Care, 14(5), 477-482. http://www.researchgate.net/profile/Serguei_Fetissov/publication/51563106_The_new_link_between_gut-brain_axis_and_neuropsychiatric_disorders/links/54d4e6c20cf2970e4e63dab0.pdf
Pärtty, A., Kalliomäki, M., Wacklin, P., Salminen, S., & Isolauri, E. (2015). A possible link between early probiotic intervention and the risk of neuropsychiatric disorders later in childhood: a randomized trial. Pediatric research, 77(6), 823-828.