Posted by & filed under Abnormal Psychology, Anxiety OC PTSD, Clinical Neuropsychology, Consciousness, Depression, Legal Ethical Issues, Neuroscience.

Description: Even if you are not old enough to have experienced the 1960’s and 70’s personally you are no doubt aware that one of the things that era was known for is the illicit use of drugs and of psychedelics like LSD, peyote, mescaline and magic mushrooms. Within what was referred to as counterculture (outside of the mainstream or the “establishment”) they were referred to as mind expanding substances. The idea was that use of such substances could open one’s mind up to a broader, deeper perception of reality. Beyond recreational use there were also, later reveled, “experiments” conducted on mental patients with the interest and support of the CIA that were not intended as investigation of their potential healing capacities but more as investigations of their potential for use in interrogation procedures. Nothing about those uses of psychedelic drugs sound particularly ethical or useful, right? So, given this, would it surprise you to learn that the state of Oregon has provided limited approval for the use of magic mushrooms in clinical settings under the supervision of clinical therapists for the treatment of things from anxiety and depression to smoking cessation? Want to find out more about these uses and about what brain scans are showing about how they work? Well, then read the article linked below to find out.

Source: Can Magic Mushrooms Heal Us? Ezra Klein, Opinion, The New York Times.

Date: March 18, 2021

Photo Credit:  Image by Scotty Frey from Pixabay

Article Link: https://www.nytimes.com/2021/03/18/opinion/oregon-psychedelic-therapy.html

So did it surprise you to read that what is being tried in Oregon is not so much a modern turn in the exploration of psychedelics in general psilocybin mushrooms in particular but a revisitation of work done in the 1950’s and 60’s on these same questions? The biggest consideration is that Oregon is not simply looking at legalization (magic mushrooms cannot be sold retail) and nor are they looking at reducing harms associated with a war on drugs approach to magic mushrooms. Rather they are building on the idea that the carefully managed use of magic mushrooms in clinical settings with clinical supervision has the potential to contribute to powerful, positive life change. What do you think? It is not the 1960’s “flower power” but perhaps a new mushroom power (and NOT a Super Mario version at that)!

Questions for Discussion:

  1. What has Oregon actually done with regards to Psilocybin mushroom use?
  2. What impact do Psilocybin mushrooms have in the brains of those who inject them?
  3. What sorts of clinician/therapeutic ethical issues should be considered in relation to the therapeutic use of Psilocybin mushrooms?

References (Read Further):

Slate Star Codex Is There A Case For Skepticism Of Psychedelic Therapy? Link

Davis, A. K., Barrett, F. S., May, D. G., Cosimano, M. P., Sepeda, N. D., Johnson, M. W., … & Griffiths, R. R. (2020). Effects of psilocybin-assisted therapy on major depressive disorder: a randomized clinical trial. JAMA psychiatry. Link

Keim, Brandon (2014) Science Graphic of the Week: How Magic Mushrooms Rearrange Your Brain, Wired. Link

Kaertner, L. S., Steinborn, M. B., Kettner, H., Spriggs, M. J., Roseman, L., Buchborn, T., … & Carhart-Harris, R. L. (2021). Positive expectations predict improved mental-health outcomes linked to psychedelic microdosing. Scientific reports, 11(1), 1-11. Link

Aday, J. S., Davis, A. K., Mitzkovitz, C. M., Bloesch, E. K., & Davoli, C. C. (2021). Predicting Reactions to Psychedelic Drugs: A Systematic Review of States and Traits Related to Acute Drug Effects. ACS Pharmacology & Translational Science. Link

Yaden, D. B., & Griffiths, R. R. (2020). The Subjective Effects of Psychedelics Are Necessary for Their Enduring Therapeutic Effects. ACS Pharmacology & Translational Science. Link

Garcia-Romeu, A., Barrett, F. S., Carbonaro, T. M., Johnson, M. W., & Griffiths, R. R. (2021). Optimal dosing for psilocybin pharmacotherapy: Considering weight-adjusted and fixed dosing approaches. Journal of Psychopharmacology, 0269881121991822. Link

McCoy, A. W. (2007). Science in Dachaus shadow: HEBB, Beecher, and the development of CIA psychological torture and modern medical ethics. Journal of the History of the Behavioral Sciences, 43(4), 401. Link

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